Effect of Moringa Oil and Flaxseed Oil on Lipid Profile of Male Rats Exposed to Carbendazim

Authors

Muhammad Hashim, Department of Biological Sciences, King Abdulaziz University, Jeddah, Saudi ArabiaFollow
Isam M. Abu Zeid, Department of Biological Sciences, King Abdulaziz University, Jeddah, Saudi Arabia; Centre of Excellence in Bionanoscience, King Abdulaziz University, Jeddah, Saudi Arabia AND Princess Doctor Najla Bint Saud Al Saud Distinguished Research Center for Biotechnology, King Abdulaziz University, Jeddah, Saudi Arabia
Atef M. Al-Attar, Department of Biological Sciences, King Abdulaziz University, Jeddah, Saudi Arabia AND Centre of Excellence in Bionanoscience, King Abdulaziz University, Jeddah, Saudi Arabia

Abstract

Carbendazim (CBZ), a commonly used fungicide, has been linked to adverse effects on the lipid profile. This study investigated whether Moringa and Flaxseed oils could mitigate CBZ-induced toxicity in male rats. Sixty male rats were divided into six groups: control, CBZ (200 mg/kg) treated, CBZ + Moringa Oil, CBZ + Flaxseed Oil, Moringa treated, and Flaxseed Oil treated. The oils were administered at 800 mg/kg for six weeks. Lipid parameters, including total cholesterol (TC), triacylglycerols (TG), low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), and high-density lipoprotein (HDL), were analyzed. CBZ elevated TC, TG, LDL, and VLDL levels, while reducing HDL. Moringa and Flaxseed oils effectively ameliorated these alterations, suggesting their therapeutic potential against CBZ-induced lipid profile disruptions.

First Page

24

Last Page

32

Recommended Citation

Hashim, Muhammad; Zeid, Isam M. Abu; and Al-Attar, Atef M. (2025) "Effect of Moringa Oil and Flaxseed Oil on Lipid Profile of Male Rats Exposed to Carbendazim," The Journal of King Abdulaziz University: Science: Vol. 1: Iss. 1, Article 3.
DOI: https://doi.org/10.64064/1658-4252.1002

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